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Investigating novel treatments for a brighter tomorrow

See Enrolling Studies

Clinical trials are carefully designed research studies that explore if a new medication or device is safe and effective for humans. These studies may also show which medical approaches work best for certain illnesses or groups of people.

Uptown Research Institute is currently enrolling patients in clinical trials for the following:

Anxiety

Anxiety Outpatient – MindMed-300

This study is designed to evaluate the efficacy of a single dose of 100 µg of MM-120 (D-lysergic acid diethylamide D-tartrate), versus placebo, for the treatment of anxiety symptoms.
This study is sponsored by Mind Medicine, Inc.

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Depression

Depression Outpatient – MindMed-310

This study is designed to evaluate the efficacy of a single dose of 100 µg of MM-120 (D-lysergic acid diethylamide D-tartrate), versus placebo, for the treatment of depression symptoms.
This study is sponsored by Mind Medicine, Inc.

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Depression

Depression Outpatient – Compass-006

Do you continue to experience depressive episodes, despite having tried more than one anti-depressant medication?

This study is designed to investigate the efficacy of COMP360 (25 mg compared to 1mg), administered with psychological support in improving symptoms of depression.

This study is sponsored by Compass Pathways.

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Depression

Depression Outpatient – Cybin 003-002

For adults with a diagnosis of Major Depressive Disorder (MDD) currently experiencing a Major Depressive Episode (MDE).

The goal of this study is to evaluate the efficacy, safety, and tolerability of CYB003 15 mg, compared to placebo, in treating symptoms of MDD in adult participants.

This study is sponsored by Cybin.

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Obesity

Obesity Outpatient – Viking 2745-301

For adults living with obesity, or adults who are overweight with at least one comorbidity.

The goal of this study is to demonstrate that VK2735 12.5 mg and/or 17.5 mg QW is superior to placebo for % change in body weight.

This study is sponsored by Viking Therapeutics.

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OCD

OCD Outpatient – Biohaven-302

Do you have OCD and are struggling to find effective treatment?

This study is evaluating the efficacy of a new medication as adjunctive therapy compared to placebo in subjects with OCD who have had an inadequate response to their current OCD treatment. Study sponsored by Biohaven Pharmaceuticals in collaboration with NOC

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Schizophrenia

Schizophrenia Inpatient – Maplight-007C-MA

For adults with schizophrenia who warrant inpatient hospitalization.

The goal of this study is to assess the efficacy, safety, and tolerability of ML-007C-MA compared with placebo in reducing symptoms of schizophrenia in adults experiencing an acute exacerbation of psychosis.

This study is sponsored by Maplight Therapeutics.

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Schizophrenia

Schizophrenia Inpatient – Neurocrine-3029

For adults with schizophrenia who warrant inpatient hospitalization.

The goal of this study is to assess the efficacy, safety, and tolerability of NBI-1117568 in adults with schizophrenia.

This study is sponsored by Neurocrine Biosciences, Inc.

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Schizophrenia

Schizophrenia Inpatient – Otsuka-00035

Treatment for worsening of symptoms in patients with schizophrenia.

The primary objective of this study is to evaluate the efficacy, safety, and tolerability of SEP-363856 (75 mg to 100 mg /daily) compared to a placebo in adults experiencing an acute exacerbation of schizophrenia.

This study is sponsored by Otsuka Pharmaceutical.

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Schizophrenia

Schizophrenia Cognition Outpatient – Alto-101-201

For adults with cognitive impairment associated with symptoms of schizophrenia

The goal of this study is to evaluate the efficacy, safety, and tolerability of ALTO-101T (transdermal patches) versus placebo in normalizing EEG (electroencephalogram) cognitive processing markers and cognition itself.

This study is sponsored by Alto Neuroscience.

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Uptown Research Institute offers an array of clinical trials across a variety of psychiatric and medical conditions.

Clinical researchers

We follow ethical and legal guidelines to meet FDA requirements, protect patient volunteers, preserve the integrity of the study, and ensure privacy.

In order to participate in a clinical trial, patients must sign an Informed Consent Form. This document describes the rights and responsibilities for participants, including the voluntary nature of participation.

Criteria For Enrollment

Not every person can participate in a clinical trial. All clinical trials have guidelines regarding who can participate, such as:

Checkmark

Inclusion Criteria, or factors that allow someone to participate in a clinical research trial

Exclusion

Exclusion Criteria, or factors that exclude someone from participation in a clinical research trial

Inclusion and exclusion criteria may include factors like:

Age

Age

Type and stage of disease

Type and stage of disease

Previous treatment history

Previous treatment history

Other medical conditions

Other medical conditions